Research line
Molecular mechanisms of neuroinflammation in neurodegenerative diseases.
- Identification of pathophysiological processes present in neurological disorders such as stroke, Alzheimer’s disease or amyotrophic lateral sclerosis (ALS).
- Molecular and cellular mechanisms of neuroinflammation in neurodegenerative diseases.
- Identification of new therapeutic targets for ALS.
Capacities
- Disease / disorder characterization: ALS, Alzheimer’s disease
- Treatment discovery: Animal models and cell cultures
- Assessment of new treatments: Animal models and cell cultures
- In vitro models: Glial & neuronal primary cultures and cell lines
- In vivo models: ALS transgenic mice, stereotaxic injection
- Others: Massive sequence analysis
Keywords: neuroinflammation, translational research, neurodegeration, neuroprotection, drug discovery, animal models.
Contact
Dr. Nicole Mahy
nmahy (at) ub.edu