Research line

Molecular mechanisms of neuroinflammation in neurodegenerative diseases.

 

  • Identification of pathophysiological processes present in neurological disorders such as stroke, Alzheimer’s disease or amyotrophic lateral sclerosis (ALS).
  • Molecular and cellular mechanisms of neuroinflammation in neurodegenerative diseases.
  • Identification of new therapeutic targets for ALS.

Capacities

 

  • Disease / disorder characterization: ALS, Alzheimer’s disease
  • Treatment discovery: Animal models and cell cultures
  • Assessment of new treatments: Animal models and cell cultures
  • In vitro models: Glial & neuronal primary cultures and cell lines
  • In vivo models: ALS transgenic mice, stereotaxic injection
  • Others: Massive sequence analysis

 

Keywords: neuroinflammation, translational research, neurodegeration, neuroprotection, drug discovery, animal models.

Contact

 

Dr. Nicole Mahy

nmahy (at) ub.edu