Research line:
Neural and endocrine secretory pathways in normal and pathological conditions.
- Studies on biogenesis, trafficking and exocytosis of secretory organelles and excitation-secretion coupling.
- Identification of alteration of secretory processes in neural and endocrine cells in human diseases.
- Identification of new brain biomarkers for human diseases.
Capacities
- Disease / disorder characterization: Cellular and molecular alterations
- Assessment of new treatments: Animal models
- Methods for diagnostic: Brain and cerebrospinal fluid analysis in mice and humans
- In vitro models: Primary cultures and cell lines
- In vivo models: Normal and genetically modified mice
- Development of new tools / technologies / computational methods: Biochemical and imaging secretion assays
Keywords: secretion, Alzheimer, calcium, cerebrospinal fluid, exocytosis, biomarker.
Contact
Dr. Fernando Aguado
faguado (at) ub.edu
